Nuphedrine is an over-the-counter (OTC) diet pill with “clinically proven weight loss technology”. According to the official website for this product at the time that this review was written, it is the “only pill to bring you both: real certified South African Hoodia & Patented Advantra-Z”. It was designed to help you burn more calories every day, enhance the ratio of lean muscle, reduce weight, stimulate thermogenesis, suppress your appetite, and boost athletic performance when used in conjunction with diet and exercise.
When this review was written, Nuphedrine contained the following ingredients within its proprietary formula: Advantra-Z (citrus aurantium), Hoodia Gordonii, and Slimaluma (caralluma fimbriata). 3 capsules make up one serving and each serving contains 1500mg of the proprietary blend.
Users are instructed to either follow the directions on the bottle or the directions of their healthcare provider when taking Nuphedrine. The product’s directions are to take 3 capsules daily with plenty of water: 2 capsules should be taken in the morning on an empty stomach and 1 capsule should be taken in the afternoon. In addition, keep in mind that for optimal results, this diet pill should be used alongside conventional weight loss methods, including a calorie-conscious diet and regular exercise.
While Nuphedrine does contain ingredients that have been clinically researched by scientists to determine their effects and how they work in the body, these ingredients have never been clinically proven to cause weight loss.
What is known about Advantra-Z, which is a patented version of the herb citrus aurantium (bitter orange) is that it works on the central nervous system and increases heart rate, which can help to boost metabolism. This may lead to more fat burning, particularly when combined with physical exercise. It’s effects are due to synephrine, a natural occurring stimulant found in citrus aurantium. That said, some research has found that because of synephrine’s ability to increase heart rate and raise blood pressure, it may not be safe to use as a dietary supplement as it could have harmful effects in some people, including serious cardiovascular effects (heart attack, stroke, etc.), particularly when combined with other stimulants such as caffeine.
Simaluma is believed to help suppress appetite. Some research has found that caralluma fimbriata – a cactus plant – may help to assist in the reduction of hunger, which can lead to a reduced calorie intake. However, no research has found this herb to have any measureable effect on weight loss.
Hoodia has long been touted as an appetite suppressant used for centuries by South African bushmen, but not clinical study has ever proven that the herb – regardless of its level of purity – suppresses hunger.
Due to this product containing citrus aurantium, prior to taking Nuphedrine, it is recommended that you consult with your healthcare provider to make sure that this is a safe product for you. This is especially important if you are currently taking medications or other supplements or if you have a medical condition or are pregnant, nursing or planning to become pregnant.