PhenRx claims to provide individuals seeking weight loss with appetite suppression, energy enhancement, mental focus, fat burning, enhanced metabolic function, a significantly lowered body mass index (BMI) and “extreme weight loss”. The official Nexgen Biolabs product page says that the PhenRx formula can increase metabolism, significantly curb appetite, burn fat in problematic areas, and stimulate the thydroid.
At the time this review was written, one bottle of PhenRx containing 60 capsules cost $44.99. Each one of the PhenRx capsules contains 377mg of a propriety blend that is comprised of: 1,3,7 – Trimethylxanthine, Beta-Phenylethylamine, Synephrine HCL, N,N-dimethyl-4-hydroxyphenylethylamine, Schizandrol A, 5-Hydroxytryptophan, and Yohimbine HCL. Additional ingredients include Magnesium Stearate and Silicon Dioxide.
While most of these ingredients are commonly found in many OTC diet pills on the market, and some research has shown that these substances can offer some benefits for weight loss, sufficient evidence is lacking to back up claims that they are safe and effective for reducing weight. Moreover, what is particularly disappointing about the Nexgen Biolabs page for PhenRx is that a science page is provided, which goes into detail about how the product supposedly works and helps a person lose weight, but at no point does it make any specific reference to the ingredients used within its proprietary blend, nor does it cite any studies.
The recommended dosage is to take 1 capsule before lunch and 1 capsule before dinner. Users who have assessed their tolerance can take up to one more capsule per day if they require additional appetite suppression.
This dosage recommendation instantly raises some red flags. The reason is that based on the ingredients list provided in the supplement facts sheet, PhenRx contains multiple stimulants including 1,3,7 – Trimethylxanthine (caffeine), Yohimbine HCL, and Synephrine. Since it contains more than one stimulant ingredient, it increases the risk of side effects, such as insomnia, anxiety, jitters, mood swings, headache, etc. Considering it is recommend that you take 1 capsule before dinner, it seems more likely that you would increase your chances of having difficulty sleeping.
Moreover, synephrine is a stimulant found in bitter orange and the FDA has warned that it can lead to severe cardiovascular side effects in certain individuals, including increased blood pressure, fainting, stroke and heart attack, especially when used in combination with caffeine.
It would be wise to first speak with your doctor before taking PhenRx, particularly if you have sensitivities to stimulants, are currently taking other medications or supplements, or if you have a medical condition.