According to the official product page, Fenphedrine was created to inhibit neuropeptide Y (NPY) and stimulate Cocaine Amphetamine Regulatory Transcript (CART) to help aid with weight loss. 

The Power of CART Over NPY

The official product page says that CART aids in:

  • Boosting metabolism
  • Reducing appetite
  • Increasing insulin levels

All this supposedly results in less storing of fat and calories and provides muscles with the energy they actually require.

That being said, NPY is a stress hormone that:

  • Lowers body temperature
  • Boosts appetite
  • Hinders metabolism

According to the site, the continual battle between CART and NPY is the reason why a person is overweight. That being said, they offer no science to back this up. 

Fenphedrine Ingredients are a Mystery

The only ingredients listed in the Fenphedrine formula include:

  • DiCaffeine Malate
  • Razberi K
  • Thermodiamine

No other ingredients are provided, and no supplements facts sheet is available for viewing on the official page, which is quite disappointing, as it makes it difficult to learn more about the product other than what the manufacturer wants to reveal.

This immediately raises a red flag because it makes it seem as though the manufacturer doesn’t care enough about its product to provide the necessary information that allows potential customers to inform themselves. It also makes it seem as though the manufacturer has something to hide, which is never a good impression to leave.

Furthermore, while the site does provide a few details about the benefits of the three ingredients that it does list, no studies have been provided to backup claims that have been made about them.

Therefore, while these ingredients may help to stimulate thermogenesis, encourage mental alertness and focus, boost energy levels, burn fat, and lower fat absorption, as the site claims, there is no proof that this is true, which is another red flag.

It is one thing to say that a product contains clinically researched ingredients and to talk about certain benefits that may help support a person’s weight loss efforts, but it is entirely another to make bold claims about the ingredients without backing up these claims with scientific fact.   

There is No Guarantee that this Product is Safe

In addition to there being no substantial evidence that Fenphedrine is effective, there is also no guarantee that it is safe. This product has a high stimulant content, which may increase the risk of certain adverse effects, such as:

  • Insomnia
  • Jitters
  • Headaches
  • Nervousness
  • Anxiety
  • Digestive upset

The risk of these adverse effects is increased in some people with sensitivities to stimulants or those who might ingest other foods or beverages containing stimulants like caffeine, while taking this product.

It would be in your best interest to first speak with your doctor before taking this product to make sure that it is safe for you and that it is beneficial to your weight loss goals. This is especially important if you are currently taking other medications or supplements or if you have an existing medical condition. After all, the last thing you want is for this diet pill product to make a medical condition worse or negatively interact with other medications or supplements that you may be taking.

With that said, when this Fenphedrine review was written, a one month supply (60 capsules) cost $69.95. It also came with a 90-day money-back guarantee.

October 2019 Update – Fenphedrine is no longer available nor is the official webpage that was dedicated to it currently active. Although you may have hoped to have tried this product, considering the lack of information about it when it was available, it’s not too surprising that it was discontinued and pulled from the digital shelves. It would be far better for you to choose an OTC diet pill that is manufactured by a reputable company that provides detailed information about their product as well as one that cites clinical research pertaining to the ingredients that have been chosen for the formula. You deserve no less than the best.

Phentagen Phenermine

Phentagen, also referred to as Phentagen Phenermine, is an over-the-counter (OTC) diet pill manufactured by Clementine Health. The claim is that it is a potent dietary supplement that contains “3 designer extracts” and other nutrients. It supposedly works by suppressing the appetite, increasing the conversion of food to energy rather than fat, and enhancinng mood as well as feelings of wellbeing.

Another claim is that Phentagen directly affects hormones by boosting the activity of the C-A-R-T hormone, which supposedly boosts metabolism and regulates hunger. It is also said to decrease the activity of the stress hormone NP-Y, which has been linked to obesity.

Although the product has been created as an OTC alternative to prescription diet drugs like Phentermine, it is unlikely to provide users with the same appetite suppressant results as the prescription medication it is attempting to emulate.

That being said, its formula contains Infinity DiCaffeine Malate, Chocamine, Green Tea Extract, Citrus Aurantium, Bioperine. Here’s how some research suggests that these ingredients may be beneficial to those seeking to lose weight:

Infinity DiCaffeine Malate is a proprietary blend containing caffeine and malic acid and is said to promote mental focus and stimulate thermogenesis. Green Tea is thought to enhance metabolism. Citrus aurantium (bitter orange) contains synephrine, a stimulant that is believed to be a thermogenic and improves the effects of caffeine. Bioperine can boost the body’s ability to absorb nutrients. Chocamine is also a proprietary blend composed of theobromine and it is said to be less potent than caffeine but also increases energy.

Although there is sufficient evidence to prove that caffeine can boost alertness and improve exercise performance, increasing fat burning potential, there is not enough scientific fact to prove that caffeine or any of the other ingredients in the Phentagen formula will effectively lead to fat loss that results in weight reduction.

Users are instructed to take two tablets per day with a glass of water and not to exceed this dosage. However, they are not directed as to when it would be best to take these pills, how to take them, or if they should be taken together or separately. Since Phentagen does contain caffeine and other stimulants, it would be prudent to avoid taking these pills late in the afternoon to prevent sleep disturbances or insomnia.

In addition to the risk of caffeine-related side effects including sleeplessness, jitters, rapid heartbeat, headache, etc., this supplement also contains synephrine, a stimulant that boosts both the good and bad effects of caffeine. Combining these two ingredients could lead to serious cardiovascular side effects, even in healthy individuals, such as increased blood pressure, fainting, stroke and heart attack.

When this review was written, there was no official product page for Phentagen Phenermine. Though it could be found for sale online at eBay for £29.95 ($42.00), even Amazon no longer carried it. This is likely an indication that the product has been discontinued.

Due to the fact that Phentagen is not easy to obtain, the fact that there is a lack of evidence that this supplement effectively works as a weight loss aid, and due to the potential risks associated with it, you are likely to find better OTC weight loss phentermine alternatives on the market. Talk to your doctor about your weight loss goals and your options. It is unwise to take any diet pill without first consulting with your healthcare provider.


Fenphedra claims to provide weight loss benefits that are not unlike those that would be experienced by taking weight loss drugs, such as Phentermine. According to the official product page for Fenphedra, at the time this review was written, the formula’s ingredients contain: Green Coffee Bean, Chromax, DiCaffeine Malate, and Phenylethylamine (PEA). If there are other ingredients they have not been provided and no supplement facts sheet is available on the site.

Although this product contains well known and popular ingredients commonly used in the OTC weight loss market, unfortunately, in spite of their popularity, there is very little proof that they are effective for causing or helping a person lose weight.

For instance, the first ingredient mentioned is green coffee bean. This ingredient gained popularity mainly because it was mentioned on the Dr. OZ show. That being said, although it has been touted as a weight loss miracle, the reality is studies conducted on the substance are insufficient. In short, there is no solid evidence that it is either effective or safe for those seeking to lose weight.

Another important aspect about Fenphedra that should be pointed out is that this supplement contains more than one stimulant, including green coffee bean, PEA, and dicaffeine malate. The more stimulants a formula contains, the greater the risk of unwanted side effects, such as sleeplessness, anxiety, jitters, headache, mood changes, etc. Anyone who has sensitivities to stimulants or caffeine should avoid taking this product. Moreover, those who do take it should reduce the amount of caffeine they ingest from foods and beverages or abstain from them altogether while taking these pills.

That being said, the safest course of action is to speak with your healthcare provider before taking this product to ensure that it is safe for you. No one should take this product without first consulting with their doctor if they have an existing health condition, are pregnant, nursing, or are taking other medications or supplements.

At the time this review was written, a 30-day supply of Fenphedra cost $69.95 plus shipping and was backed by a %100 money-back guarantee. The suggested dosage is one capsule 30 minutes before breakfast and one 30 minutes before lunch.