Phenelean is marketed as a thermogenic formula that promotes appetite suppression and delivers maximum energy. It comes from Orb Pharmaceuticals. The claim is that its formula is made with strong pharmaceutical grade ingredients and that it has “great thermobolic stimulation and fat burning.”

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Lipozene MetaboUP Plus

Lipozene MetaboUP Plus is a dietary supplement formulated to support weight management efforts by helping to increase metabolism and boost energy. It is a product from Obesity Research Institute LLC, the makers of the popular OTC diet pill Lipozene.

Exclusive Thermogenic Blend

Lipozene MetaboUP Plus advertises that it has an exclusive thermogenic blend. However, simply because something is “exclusive” does not mean that it is good, safe or effective. It simply means that the manufacturer is claiming that no other diet pill has the same exact formula.

When this Lipozene MetaboUP Plus review was written, the formula included the following ingredients:

  • Vitamin B6
  • Vitamin B12

Proprietary Blend

  • Green Tea
  • Guarana Seed
  • Caffeine
  • Oolong Tea
  • Kola Nut
  • Cayenne
  • Platycodon Root

Lipozene MetaboUP Plus Contains Multiple Doses of Caffeine

This nonprescription diet pill contains several ingredients that are considered to be thermogenics and can help boost metabolism and energy, most notably caffeine. Beyond actually listing caffeine as an ingredient, the formula includes several ingredients that contain caffeine including green tea, guarana, Oolong tea, and kola nut.

On the positive side, caffeine can produce thermogenic effects and has been found to help boost mental alertness. In fact, according to some research, caffeine at commonly consumed doses can have a notable influence on energy balance and may help to promote thermogenesis in the treatment of obesity.

On the not so positive side, while caffeine may be helpful with energy, not only has it not be proven effective as a treatment for obesity, but too much of it can result in unpleasant side effects, such as:

  • Anxiety
  • Jitters
  • Rapid heartbeat
  • Insomnia

According to the Lipozene MetaboUP Plus supplement facts label, the total amount of caffeine per serving is 120 mg. However, it is not known if this is referring to only the listed caffeine ingredient in the formula or if this includes all the ingredients within the formula that contain it.


The recommended usage instructions are to take 2 tablets once per day with a minimum of 8 ounces of water. If there is only 120 mg of caffeine per serving (2 tablets), most healthy adults who are not sensitive to stimulants should be able to tolerate this diet pill. That being said, to avoid potential unwanted side effects it would be a good idea to take these pills earlier in the day to prevent the potential for sleep disturbances. It would also be wise to avoid taking other stimulants (beverages, food or other supplements) while taking this product to reduce the risk of negative side effects.

When this Lipozene MetaboUP Plus review was written, a single bottle sold for $25.95 on Amazon. An official product page did not exist.


Avaprex is an over-the-counter (OTC) diet pill that works to amplify energy, boost fat metabolism, stimulates fat burning, and may also help to curb hunger. The creators of the product (also called Avaprex) claim to be nutraceutical experts, who have worked hard to design a formula that contains the purest weight loss ingredients and is of the highest quality.

Avaprex is marketed as a safer and non-prescription alternative to popular prescription diet pill Adipex, brand name Phentermine. In other words, it’s just another Adipex alternative with unsubstantiated claims.

At the time that this review was written, a single bottle of Avaprex cost $90.91 on Amazon. Considering this was one of the only places it could be purchased online and due to its high price, as well as the fact that there is no official website, this is very good indication that the product has been discontinued.

Avaprex Ingredients

With that in mind, the following were the ingredients that were part of the Avaprex formula when this review was written:

  • Raspberry Ketone
  • Green Tea
  • Caffeine

Proprietary Blend:

  • Apple Cider Vinegar
  • Grapefruit
  • Kelp
  • Acai Fruit
  • African Mango
  • Resveratrol Extract

If you are familiar with popular ingredients frequently used in the OTC weight loss diet pill industry, you likely recognized many of the substances listed above. They have all be touted for their positive effects, such as fat burning, energy boosting and appetite suppression. That being said, regardless of the claims you may have heard about these ingredients, none of them have ever been proven effective in regard to leading to measurable weight loss. Moreover, Avaprex, itself, has never been clinically proven effective.

Caffeine and green tea are the ingredients with the most promise in this formula. Research has found that, in addition to boosting mental alertness, when combined with physical activity, they can help boost metabolism and fat burning. Still, due to the fact that it is unknown how much of each substance is in one serving, there’s no way of knowing just how effective it will be.

Potential Side Effects

It should also be noted that stimulant ingredients can lead to unpleasant side effects, such as headache, jitters, insomnia, etc.

You should also know that other side effects that may occur with Avaprex including:

  • Abdominal gas
  • Flushes
  • Nausea
  • Heartburn
  • Upset stomach

Be that as it may, if Avaprex is an OTC diet pill that you are considering, make sure you consult with your healthcare practitioner before you take it to make sure that it is a smart and safe option for you.

Update: November 2020

As it was assumed at the time the above Avaprex review was written, this OTC diet pill product has been discontinued. Currently, it can no longer be found online for purchase in any of its forms. Amazon still lists the product, but it is “currently unavailable”.

What to Consider Before Buying Another Adipex Alternative

Avaprex isn’t the first diet pill product to be marketed as an over the counter Adipex alternative and it won’t be the last. If you are seeking a nonprescription diet pill that can provide you with the benefits that the prescription weight loss medication phentermine can offer, you should know that no such product truly exists.

There are diet pills available that can offer you support with your weight management efforts, such as engaging in regular fitness-appropriate exercise and adhering to a healthy calorie-conscious diet. These diet pills tend to offer support in regard to fat burning, improved mental focus, boosted metabolism and energy, helping to make it easier to keep up with the efforts that will/are making a difference to your waistline.

To find the best of these weight loss supplement products make sure that the diet pills that interest you are not like Avaprex. In other words, ensure that:

  • The product has clinically researched ingredients
  • The manufacturer doesn’t make unsubstantiated claims regarding the benefits
  • There is an official website for the product
  • The price is cost competitive
  • There is a money-back guarantee

Not All Clinically Researched Ingredients are Beneficial for Weight Loss

Finally, it’s also worth noting that when you are seeking the highest quality diet pills, it’s not simply enough for a product to contain clinically researched ingredients. Beyond simply using ingredients that have been scientifically studied, it is also important to check if those ingredients have been found to have any potential positive effect on weight management. More specifically, weight loss in humans.

For instance, the main ingredient in Avaprex is Raspberry Ketone. This ingredient is a well-known antioxidant and many believe that this chemical from red raspberries can help with obesity. Although it has been studied, and some research involving animals or test tubes have shown that this ingredient may possibly increase metabolism, boost the rate at which the body burns fat, and lower appetite, there is no reliable clinical evidence that raspberry ketone helps in the improvement of weight loss in humans.

As such, it is important to make sure that the ingredients used in the OTC diet pills that interest you have not only been clinically researched, but that the findings of this research (conducted on human subjects) offer some support to the benefit claims the manufacturer has made about this product.

Phen Caps 37.5 for Women

Phen Caps 37.5 for Women is marketed as a fat burner that has been specially formulated for women who are seeking to lose weight. It is made in the USA and comes from CHI Nutrition. It claims to be a premium grade dietary supplement and can be purchased from Amazon for $39.99.

What Benefits Can You Expect?

Although there was no official product page when this Phen Caps 37.5 for Women review was created, according to the Amazon sales page, users who take this diet pill can expect to experience certain benefits, such as:

  • Advanced appetite suppression
  • Help with reducing hunger cravings
  • Thermogenic fat burning
  • Boosted metabolism
  • Enhanced energy levels throughout the day

Of course, the only real way to know if this diet pill can provide these potential benefits is to check out its ingredients list.

Phen Caps 37.5 for Women Ingredients

According to the supplement facts listed on the pink and white bottle label, the formula was composed of:

  • Green Coffee Bean
  • Raspberry Ketones
  • Garcinia Cambogia
  • Caffeine Anhydrous
  • Green Tea

Each of these ingredients are well known in the over the counter (OTC) weight loss pill market. Several studies have found that some of them may have thermogenic effects, which could be advantageous to those who are seeking to burn fat.

For instance, certain studies have suggested that by using caffeine on a regular basis in the correct amounts can help obese patients lower their body fat levels and lose weight with greater effectiveness than those who did not take caffeine regularly. This was attributed to caffeine’s ability to promote thermogenesis, a process in the body that is believed to help increase metabolic rate, which can burn fat and calories at a more rapid rate.

This Product Contains Caffeine

In addition to containing caffeine anhydrous, there is also caffeine present in green coffee bean and green tea. Since this is the case, it is recommended that anyone who has a sensitivity to stimulants should avoid taking this weight loss aid.

Moreover, if you do decide to take Phen Caps 37.5 for Women, not only should you speak with your health care provider first, but you should avoid ingesting other products with caffeine or other stimulants to lower your risk of experiencing unpleasant side effects, such as:

  • Jitters
  • Anxiety
  • Rapid heartbeat
  • Sleep disturbances

Finally, it should be noted that beyond saying that the diet pill is for women and making the label a stereotypical pink, there is no indication as to what makes this dietary supplement’s particular formula well suited to women. As such, without offering any kind of justification, one can only assume that it is simply a marketing strategy and the product itself has absolutely nothing unique to offer women who are seeking help with their weight loss compared to other OTC diet pills.  This calls the manufacturer’s integrity into question, and, as a result, the quality of the Phen Caps 37.5 for Women product as well.

Phenastin NAEX

Phenastin NAEX is a type of diet pill designed for individuals who are seeking a non-prescription product, who would like something to help them with their weight loss strategies and who do not want to take a product that contains stimulants.

Benefits of Phenastin NAEX

This natural weight loss aid claims to provide many benefits. Among these benefits include:

  • Powerful appetite suppression
  • Blood sugar stabilization
  • Improvement of lipid metabolization
  • More weight loss compared to diet and exercise alone
  • Stimulant-free

Being a stimulant-free product, Phenastin NAEX can be taken later in the day as it does not contain ingredients that can lead to sleep disturbances. Moreover, it should also not cause side effects such as jitters, anxiety, rapid heartbeat, etc. As such, this may make it more of an ideal product for individuals who are sensitive to high quantities of stimulant ingredients like caffeine. 

Key Ingredients

The key Phenastin NAEX ingredients within the formula include:

  • Green Tea
  • Gymnema Sylvestre
  • Griffonia Simplicifolia
  • Caralluma Fimbriata
  • Dandelion Extract
  • Grains of Paradise

On the plus side, each of those ingredients are well known within the over-the-counter diet pill industry and they have been clinically studied. For instance, some studies have found that green tea may lower the amount of fat you absorb from foods and gymnema sylvestre, which is believed to have potent anti-diabetic properties, may work to suppress sweetness, helping to reduce sugar cravings.

On the down side, the ingredients have not been clinically proven effective for weight loss so there is no guarantee that they will live up the manufacturer’s claims.

Furthermore, it should be noted that this product does actually contain caffeine, which exists in green tea. That being said, it is likely only a very small amount which isn’t likely to produce stimulant effects. This is why the manufacturer has labeled it “stimulant-free” and not “caffeine-free.”

Order a Trial Pack

When this Phenastin NAEX review was created, a single bottle could be purchased on the official product page for $34.99, and was also available in other package formats. Not only that, but you could also purchase a 7-day trial pack to find out if it was right for you. There were two trial options. You could buy only Phenastin NAEX for a one-time fee of $9.99 and free shipping or you could buy this diet pill and the original Phenastin (which does contain stimulants) for $13.99 and free shipping.

While the trial packs are a great way to test to see if this product is right for you, always remember that speaking with your doctor is a good idea. This is particularly important if you have a known medical condition and are currently taking medications to treat health issues.

Slimple Appetite Suppressant

Slimple Appetite Suppressant is a diet pill that has been developed to offer those who take it weight control, increased metabolism and energy maintenance. It is created by an American-based company and is part of the “Slimple Trinity Diet,” which features two other dietary supplements: “Slimple Daily Cleanse” and “Slimple Diet Spray.”

Slimple Appetite Suppressant Benefits

As is common with most weight management aids designed for the over-the-counter (OTC) diet pill market, the manufacturer of this supplement claims that this product offers dieters will a variety of benefits. Among these include:

  • Hunger Control – The Slimple Appetite Suppression formula includes a variety of ingredients that are supposedly known for their appetite suppressing properties and their ability to leave a person with a sense of fullness.
  • Combats fatigue – Low energy is one of the top struggles among those who wish to lose weight. This diet pill’s key ingredient is Decocainized Cocoa Leaf Extract. Cocoa leaf is a stimulant and can help a person power through their day.
  • Stress relief – This nonprescription diet pill contains an ingredient known as Chuchuhuasi, which is believed to support the adrenal system, helping to lower cortisol, also known as the stress hormone. When you are less stressed, you are more likely to make better dietary choices and/or stick to your healthy diet plan.
  • Boost exercise drive – When you’re not feeling fatigued and stressed, you’re naturally more motivated to get up and move.  

Slimple’s key ingredients

When this Slimple Appetite Suppressant review was written, the official site for the product claimed that “Slimple gives you real results that you can see and feel without the risk.” The risk that is being implied here is the risk of unpleasant side effects associated with prescription diet drugs, such as phentermine. With statements such as these, it seems that the manufacturer of this product is attempting to market this dietary supplement as a phentermine alternative.

That being said, the key Slimple Appetite Suppressant ingredients include:

  • Annatto Leaf Powder
  • Decocainized Cocoa Leaf Extract,
  • Maca Root,
  • Citrus Bioflavonoids,
  • Guggul (gum extract),
  • Green Tea,
  • Lotus Leaf Extract,
  • Cassia Nomame

None of these ingredients have been proven effective or safe for weight loss. Even Decocainized Cocoa Leaf Extract, which is exclusive to Slimple, has never been proven in any way to suppress appetite or boost energy to a degree that leads to long-term weight loss.

While it is likely that a person will feel less fatigue taking this product, due to the fact that it does contain this and other stimulants, there is no guarantee that it will curb appetite or help in any other meaningful way for fighting fat.

Still, should you wish to try it, when this review was written, a single bottle could be purchased on the official Slimple product page for $29.95.

Prior to taking Slimple Appetite Suppressant it would be in your best interest to first consult with your healthcare provider.


SmartSlim is an herbal supplement from Doctors Designs. This manufacturer claims to develop nutraceuticals targeted for “optimal weight loss outcomes” and provides “comprehensive weight management solutions for health professionals.” SmartSlim is supposedly a powerful blend that works on both the mind and the body.

The Primary SmartSlim Benefits for Weight Loss

This diet pill was created to help people combat hunger cravings and the feelings of wanting to consume everything that is in front of them. According to the makers of SmartSlim, many people who struggle with hunger are not actually hungry. It isn’t food that they crave but the feeling of a “reward response.” However, this is mistaken for hunger, which leads to people consuming more food than they need.

With this in mind, SmartSlim has been made to address this “reward response” by offering benefits including:

  • Thermogenesis
  • Craving Support
  • Mind support

A Look at the SmartSlim Ingredients

When this SmartSlim review was created, the formula was composed of the following ingredients, which were part of a Proprietary Blend:

  • Green Tea,
  • Bitter Orange,
  • Velvet Bean,
  • Sweet-scented Geranium,
  • Sacred Lotus leaf,
  • Nutmeg

In regard to the effectiveness of these ingredients, while they each have been clinically researched, scientists have yet to prove their effectiveness for causing or aiding in weight loss in a meaningful way. Even green tea, which has long been praised for its positive benefits regarding weight loss, is not proven as WebMDWebMD shows there is insufficient evidence regarding obesity research.

Moreover, it is important to note that SmartSlim contains bitter orange which contains the simulants synephrine and octopamine. Although these stimulants have been found to be beneficial for exercise performance in some cases, when combined with caffeine, they can be dangerous.

However, it appears that the only caffeine in SmartSlim is in green tea. Typically, the amount of caffeine in green tea is a minimal amount.

Should You Take SmartSlim?

If you are seeking a non-prescription Phentermine alternative, it is unlikely that SmartSlim will do the trick. There is no evidence to back up the claims that this product can offer craving support. Furthermore, the formula has not been evaluated or approved by the FDA and contains bitter orange, which has a reputation of causing negative side effects.

It would be in your best interest to speak with your healthcare professional if you are interested in taking this diet pill. This is particularly prudent if you are pregnant or nursing, have a known health condition, or are currently taking any medications or supplements to treat a medical issue.

When this review was created for SmartSlim, it could be purchased on Amazon for $49.89.

Weight Loss Pills and Supplements Reviews 

Appetite Away

Appetite Away is a dietary supplement from 4 Organics that claims to be an natural diet pill that provides users with control over hunger without jitters. Beyond appetite control it offers other potential advantages like increased fat burning, boosted metabolism, decreased fat storage, and provides key nutrients.

More specifically, the supposed benefits of Appetite Away include boosted energy levels, increased stamina, enhanced metabolism, increased conversion of glucose into energy, burns calories and stores fat more efficiently, and works equally for both men and women.

When this review was created, the Appetite Away ingredients include: Chromium, Caffeine Anhydrous and a Proprietary Blend (Theobromine, Guarana, Hoodia Cactus Powder, caralluma fimbriata, Magnolia Bark, Green Tea, Pomegranate Powder, Maca Fisetin, L-Theanine, L-Tyrosine, Banaba, Cha de Bugre, Guggulsterone, Glucomannan).

The directions, according to the Amazon sales page, where this product could be purchased when this review was written, are to take 1-2 capsules to control hunger as needed. Users are cautioned not to exceed more than 4 capsules within a 24 hour period.

Although the Amazon sales page claims that there are no jitters, each capsule contains 200 mg of caffeine anhydrous (caffeine equivalent of about 2 cups of coffee). It also contains another caffeine stimulant, guarana.

With that in mind, if users can take up to 4 capsules per day, this would amount to 800 mg of caffeine in total, which is double the amount of caffeine (about 4 cups of coffee) that is considered safe for individuals who are not sensitive to this stimulant.

In other words, not only is Appetite Away likely to cause jitters and a slew of other unpleasant side effects (e.g. insomnia, rapid heartbeat, anxiety, upset stomach, headaches, etc.) but it could also be dangerous if you took the maximum allowable dose.

Moreover, none of the ingredients in this diet pill have ever been proven effective for weight loss. Also, there are far too many ingredients within this formula for them to be beneficial in a meaningful way, even if they were effective.

Due to there being no official product page for Appetite Away when this review was created and the amount of stimulants in this formula, it would be best for you to consider another diet pill that could help support your appetite suppression efforts, or at the very least, contained less caffeine.

That being said, if you would like to give Appetite Away a try, do speak with your doctor first to make sure it is safe for you to do so.

Kor Naturals Stim-Free Fat Burner

Kor Naturals Stim-Free Fat Burner is a weight loss supplement that supposedly works to naturally burn fat and increase energy with no jitters and crashing. It claims to help users burn fat, boost energy levels, suppress appetite, preserve muscles and amp up metabolism. More importantly, it promises to do all of this without stimulants.

Boosting energy and enhancing metabolism is a tall order for a product without stimulant ingredients, such as caffeine. With that in mind, these were the ingredients included in this diet pill formula when this Kor Naturals Stim-Free Fat Burner was written: Chromium, L-Carnitine L-Tartrate, Green Tea, Olive Leaf, Coleus Forskohli, BioPerine.

Taking a closer look at these ingredients, here’s what they are believed to do:

Chromium, an essential trace mineral is thought to positively impact fat metabolism and help to increase lean body mass. Some research has found that it may help maintain blood sugar levels, lower carb cravings and help to treat insulin resistance in the body.

L-Carnitine can help to decrease fatigue and provide more energy by lowering levels of glycogen and lactate during exercise. It is also believed to help burn fat for fuel so that it can be used by the body as an energy source.

Green tea is thought to help elevate metabolic rate, boost fat oxidation and improve insulin. It is also thought to include antioxidants that trigger norepinephrine to decompose fat cells. The belief is that with both its flavonoids and caffeine, green tea can help burn fat and calories while at the same time improving exercise performance.

Olive leaf may help to lower blood pressure, boost thyroid function, and lower blood pressure. It may also help to improve fat burning by increasing noradrenaline and adrenaline levels.

Coleus forskohli is thought to help in lowering body fat percentage and fat mass, decreasing the appearance of cellulite and preventing weight gain. It may also help to decrease blood pressure and boost lean body mass.

BioPerine is an extract from black pepper and is believed to help increase the bioavailability of nutrients in the blood. It may also assist the body in absorbing other ingredients, which is why it is often included in over-the-counter (OTC) weight management formulas.

Now, you might be wondering, if this product has green tea, doesn’t this mean it contains the stimulant caffeine? It does, but as it is a part of the green tea ingredient in this formula, it is likely not enough caffeine to produce a stimulant effect, which is why the manufacturer has made the stimulant-free claim.

All that being said, there is zero scientific proof that any of the ingredients in Kor Naturals Stim-Free Fat Burner are effective for causing weight loss or are effective for aiding in weight loss or weight management. Moreover, simply because a product doesn’t contain stimulants does not mean that it is safe to take or without side effects.

As is the case for all nonprescription diet pills, it’s a good idea to consult with a doctor before taking this product.

When this Kor Naturals Stim-Free Fat Burner review was created, a single bottle sold for $39.95 on the official Kor Naturals website.

BURN 365

BURN 365 is a low-stimulant fat burner from Mojo Supplements LLC. It is composed of a blend of premium ingredients and has supposedly been designed to naturally enhance weight loss by boosting metabolism, suppressing hunger cravings and promoting fat burning.

When this BURN 365 review was created, there wasn’t much information provided about this product. Mojo Supplements did have a webpage advertising all its available products, including BURN 365, but beyond listing the ingredients and the statement that can be found on the diet pill’s bottle label, no other details were provided.

Furthermore, in spite of there being a product page, it appears that the only place where BURN 365 can be purchased is Amazon, where it sold for $9.99 when this review was written. On the Amazon sales page, the only other details that were provided about this dietary supplement is that it can help burn fat in problem areas, such as the stomach, legs, arms, thighs, chin, hip, abs, buttocks, cellulite or body. Needless to say, all these claims made about BURN 365 are entirely unsubstantiated.

With that in mind, the ingredients in BURN 365 include: Green Coffee Bean, Raspberry Ketone, Garcinia Cambogia, Caffeine Anhydrous, Green Tea.

Some good news is that BURN 365 does not contain a huge number of ingredients, which isn’t always the case when it comes to dietary supplements that market themselves as non-prescription phentermine alternatives. What’s more, each of these ingredients is well-known in the over-the-counter (OTC) weight loss supplements industry.

Green coffee bean is thought to help enhance metabolism and burn fat. Raspberry ketone is touted as an antioxidant and is thought to help you burn body fat faster by causing the fat within cells to be broken down. Garcinia cambogia is thought to help with fat burning, fat blocking and appetite suppression. Caffeine is believed to enhance metabolism and increase mental alertness. Green tea is said to help elevate metabolic rate and increase fat oxidation.

Still, none of these ingredients are proven to cause weight loss. Additionally, in regard to their ability to aid in weight loss, there is insufficient scientific evidence to prove that they can even do that. In other words, there is no guarantee that BURN 365 will support your weight management efforts.

Finally, keep in mind that even though BURN 365 claims to be a low-stimulant product, it does still contain stimulants, which may increase the risk of certain side effects (e.g. insomnia, jitters, anxiety, etc.) in some people, especially those who are sensitive to caffeine.

Although this is not one of the strongest diet pills, still be sure to speak with your healthcare provider before taking BURN 365 to make sure that this is an ideal diet pill for you.