Lipozene MetaboUP Plus

Lipozene MetaboUP Plus is a dietary supplement formulated to support weight management efforts by helping to increase metabolism and boost energy. It is a product from Obesity Research Institute LLC, the makers of the popular OTC diet pill Lipozene.

Exclusive Thermogenic Blend

Lipozene MetaboUP Plus advertises that it has an exclusive thermogenic blend. However, simply because something is “exclusive” does not mean that it is good, safe or effective. It simply means that the manufacturer is claiming that no other diet pill has the same exact formula.

When this Lipozene MetaboUP Plus review was written, the formula included the following ingredients:

  • Vitamin B6
  • Vitamin B12

Proprietary Blend

  • Green Tea
  • Guarana Seed
  • Caffeine
  • Oolong Tea
  • Kola Nut
  • Cayenne
  • Platycodon Root

Lipozene MetaboUP Plus Contains Multiple Doses of Caffeine

This nonprescription diet pill contains several ingredients that are considered to be thermogenics and can help boost metabolism and energy, most notably caffeine. Beyond actually listing caffeine as an ingredient, the formula includes several ingredients that contain caffeine including green tea, guarana, Oolong tea, and kola nut.

On the positive side, caffeine can produce thermogenic effects and has been found to help boost mental alertness. In fact, according to some research, caffeine at commonly consumed doses can have a notable influence on energy balance and may help to promote thermogenesis in the treatment of obesity.

On the not so positive side, while caffeine may be helpful with energy, not only has it not be proven effective as a treatment for obesity, but too much of it can result in unpleasant side effects, such as:

  • Anxiety
  • Jitters
  • Rapid heartbeat
  • Insomnia

According to the Lipozene MetaboUP Plus supplement facts label, the total amount of caffeine per serving is 120 mg. However, it is not known if this is referring to only the listed caffeine ingredient in the formula or if this includes all the ingredients within the formula that contain it.


The recommended usage instructions are to take 2 tablets once per day with a minimum of 8 ounces of water. If there is only 120 mg of caffeine per serving (2 tablets), most healthy adults who are not sensitive to stimulants should be able to tolerate this diet pill. That being said, to avoid potential unwanted side effects it would be a good idea to take these pills earlier in the day to prevent the potential for sleep disturbances. It would also be wise to avoid taking other stimulants (beverages, food or other supplements) while taking this product to reduce the risk of negative side effects.

When this Lipozene MetaboUP Plus review was written, a single bottle sold for $25.95 on Amazon. An official product page did not exist.

MetaboUP Plus

MetaboUP Plus is a thermogenic fat burner that is meant to help increase energy and metabolism. It is manufactured by Obesity Research Institute LLC, a company that is well-known for creating their more popular dietary supplement for weight loss, Lipozene.

MetaboUP Plus contains ingredients that are commonly associated with promoting thermogenesis. This is a naturally occurring metabolic process within the body. During this process, the body burns calories to generate heat. Exercise, diet and environmental temperature are all elements that can trigger thermogenesis. It is commonly believed that thermogenesis can help with weight loss due to its ability to increase the body’s calorie burn.

When this MetaboUP Plus review was written, each serving size (2 tablets) contained the following ingredients: Vitamin B6 (600 mcg), Vitamin B12 (15 mcg) and a Proprietary Blend (952 mg): Green Tea, Guarana Seed, Caffeine, Oolong Tea, Kola Nut, Cayenne, Platycodon Root.

For starters, none of these ingredients have ever been proven effective for weight loss. However, each of these ingredients are believed to offer dieters certain benefits. For instance, green tea is thought to help increase energy levels and improve metabolism, while caffeine helps to increase focus, can maximize fat burning during workouts, and can help to suppress appetite in some people. Guarana is believed to help with memory and mood and alleviate fatigue, and kola nut can also help to prevent fatigue and boost thermogenesis.

In essence, many of the ingredients in MetaboUP Plus are stimulants or contain caffeine. Furthermore, it should be noted that although on the product supplement facts label it says that the total amount of caffeine is 120 mg, it is unclear if this is referring only to the listed ingredient caffeine or if it includes all caffeine that exists within the formula, such as the caffeine in green tea, oolong tea, guarana and kola nut.

It would be better if the manufacturer was clearer about its statement regarding the product’s caffeine amount per serving. The reason being is that if it contains more than 120 mg (which is only slightly more than the amount of caffeine you’d find in a cup of coffee), this is something of which users should be aware.

The recommended use is to take 2 tablets once daily with at least 8 ounces of water. Although it is not stated at what time of day it would be best to take this dietary supplement, it would probably be in your best interest to take it no later than early afternoon to avoid increasing the risk of insomnia or sleep disturbances.

When this review was written, a single bottle of MetaboUP Plus could be purchased on Amazon for $11.95. Prior to taking this dietary supplement, make sure it is a safe and ideal choice for your weight management plan.